SupplementDEX

Polycystic ovary syndrome (PCOS)

Supplements studied for polycystic ovary syndrome (PCOS).

Overview

Inositol (WA 88; high effect size, very high evidence, very high trust) has high-strength evidence for PCOS, with 25 studies showing it may modestly reduce weight, blood sugar, cholesterol, and androgen levels and increase ovulation rates, though pregnancy outcomes are less clear and it may be less effective than metformin for some measures. N-Acetyl Cysteine (NAC) (WA 68; medium effect size, very high evidence, medium trust) may improve ovulation and insulin resistance but is generally less effective than metformin.

Berberine (WA 72; medium effect size, high evidence, very high trust) and L-Carnitine (WA 72; medium effect size, high evidence, very high trust) may improve metabolic and fertility-related outcomes in some trials. Resveratrol (WA 72; medium effect size, high evidence, very high trust) has inconsistent results across studies. See the heatmap and evidence reviews below.

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SupplementDEX Database

24 supplements for , , and rated at least stars. All purchase bands. No minimum star filter.

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