SupplementDEX

Kidney failure

Supplements studied for kidney failure.

Overview

Calcium carbonate and calcium acetate have the strongest evidence for kidney failure, with high ratings across effect size, evidence, and trust. These may help lower elevated blood phosphate levels, with calcium acetate appearing more effective than sevelamer in some studies. Calcium citrate is not advised because it binds phosphate less well.

L-Carnitine has medium-strength evidence from 27 studies, though oral use is not FDA-approved and results for dialysis-related problems such as anemia response, cramps, and blood pressure are mixed. Selenium, Vitamin B9 (Folate), and N-Acetyl Cysteine (NAC) have limited or uncertain evidence. The heatmap and evidence reviews below provide a fuller comparison.

Effect graph

Subscribe to view effect graphs

Interactive visualisations of ranked conditions and clinical benefit with purchase guidance.

View plans

Already a subscriber? Sign in

Relevant supplements heatmap

Relevant supplements sorted by DEX Score.

Subscribe to view effect heatmaps

See effect size, evidence strength, and trust at a glance for every condition.

View plans

Already a subscriber? Sign in

SupplementDEX Database

6 supplements for , and rated at least stars. All purchase bands. No minimum star filter.

Subscribe to access the SupplementDEX Database

Read this and 2,600+ other evidence reviews on our practitioner plan.

View plans

Already a subscriber? Sign in

Evidence visualised

Subscribe to view condition evidence

Visual summaries of supplement evidence ranked by condition.

View plans

Already a subscriber? Sign in

On this page