Generalised anxiety disorder (GAD)
Supplements studied for generalised anxiety disorder (GAD).
Overview
Generalised anxiety disorder has three reviewed supplements with low to medium trust. Kava (WA 56; low effect size, very high evidence, medium trust; 12 studies) shows mixed results: a large 16-week trial found no advantage over placebo, and major guidelines recommend against kava for GAD based on the best available research.
Rhodiola (WA 40; low effect size, evidence, and trust) improved symptoms in one small open-label study without placebo control and should be interpreted cautiously. Vitamin D 50,000 IU weekly for three months with usual medications modestly improved anxiety versus medication alone in one small trial. See the heatmap and evidence reviews below for all three entries.
Effect graph
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Relevant supplements heatmap
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SupplementDEX Database
3 supplements for rated at least stars. All purchase bands. No minimum star filter.
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Evidence visualised
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