Diabetic Neuropathy
Supplements studied for diabetic neuropathy.
Overview
Alpha-Lipoic Acid (WA 68; medium effect size, very high evidence, medium trust; 31 studies) has the strongest support: 600–1800 mg daily may relieve burning, pain, numbness, and tingling within weeks, though nerve function tests often do not improve. Acetyl-L-Carnitine (WA 72; medium effect size, high evidence, very high trust) at 2–3 g daily may reduce pain and improve sensation, especially in newer or poorly controlled type-2-diabetes.
Coenzyme Q10 (WA 64; medium effect size, medium evidence, high trust) and Gamma-Linolenic Acid (WA 56; medium effect size, low evidence, medium trust) also show medium evidence in small trials for pain relief and nerve function when blood sugar is controlled. Inositol (WA 36; very low effect size, medium evidence, medium trust) did not help in early research. The heatmap and evidence reviews below detail all 13 supplements.
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SupplementDEX Database
14 supplements for , and rated at least stars. All purchase bands. No minimum star filter.
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