Infertility
Supplements studied for infertility.
Overview
Ten supplements are indexed for infertility (31 studies), all with low-to-modest ratings. Melatonin, N-Acetyl Cysteine (NAC), and Vitamin D share DEX Score 52 with low effect size and medium trust. Melatonin has not improved IVF/ICSI pregnancy rates despite some embryo-quality signals. NAC may improve some sperm parameters in mixed male-infertility trials. Vitamin D may increase clinical pregnancy rates mainly in deficient women, though IVF-specific outcomes are inconsistent.
Inositol (DEX Score 52; low effect size, high evidence, medium trust; 8 studies) may improve egg retrieval and fertilization before IVF but usually not pregnancy rates. Astaxanthin has very limited data. See the heatmap and evidence reviews below.
Effect graph
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Relevant supplements heatmap
Relevant supplements sorted by DEX Score.
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SupplementDEX Database
10 supplements for and rated at least stars. All purchase bands. No minimum star filter.
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Evidence visualised
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Visual summaries of supplement evidence ranked by condition.
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