Obesity
Supplements studied for obesity.
Overview
Multiple supplements show medium-strength but modest evidence for obesity. Alpha-Lipoic Acid (DEX Score 68; medium effect size, very high evidence, medium trust) may produce small weight loss of roughly 0.7–2.3 kg over weeks to months. Chromium (DEX Score 72; medium effect size, high evidence, very high trust) may yield very small weight loss without clear BMI or waist changes. Inulin (DEX Score 68; medium effect size, high evidence, high trust) may help some groups lose weight, especially with activity, though results vary.
Caffeine (DEX Score 72; medium effect size, high evidence, very high trust), often combined with other agents, may support short-term weight loss. Cissus Quadrangularis (DEX Score 52; low effect size, high evidence, medium trust) has early signals for weight and body-fat reduction with diet in some trials. Effects are generally modest. See the heatmap and evidence reviews below.
Effect graph
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Relevant supplements heatmap
Relevant supplements sorted by DEX Score.
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SupplementDEX Database
53 supplements for , and rated at least stars. All purchase bands. No minimum star filter.
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Evidence visualised
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Visual summaries of supplement evidence ranked by condition.
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