SupplementDEX

Osteoporosis

Supplements studied for osteoporosis.

Overview

Calcium (DEX Score 68; medium effect size, very high evidence, medium trust), Vitamin D (DEX Score 68; medium effect size, very high evidence, medium trust), and Vitamin K (DEX Score 68; medium effect size, very high evidence, medium trust) have medium-strength evidence supporting bone health in osteoporosis. Calcium with adequate vitamin D may slow age-related bone loss; vitamin D with calcium may reduce hip and other fractures in adults over 50, though effects vary by population. Vitamin K may modestly reduce fractures and spine bone loss when combined with other nutrients, with mixed hip outcomes.

Nattokinase (DEX Score 68; medium effect size, very high evidence, medium trust) is listed for soy isoflavone research suggesting possible bone-density benefits post-menopause. Black Tea (DEX Score 68; medium effect size, high evidence, high trust) regular intake may be linked to stronger bones and lower hip fracture risk in long-term drinkers. The heatmap and evidence reviews below compare evidence.

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SupplementDEX Database

18 supplements for , and rated at least stars. All purchase bands. No minimum star filter.

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