Migraine
Supplements studied for migraine.
Overview
Caffeine combined with pain relievers like acetaminophen and aspirin has high-strength evidence for acute migraine treatment across 10 studies. Melatonin at 3 to 4 mg in the evening, Vitamin B2 (Riboflavin) at 100 to 400 mg daily, and Coenzyme Q10 at 100 to 400 mg daily have medium-strength evidence for prevention, reducing attack frequency, duration, or severity.
Vitamin D supplementation shows preliminary but uncertain preventive benefit in small trials. The heatmap and evidence reviews below compare these options across 70 studies.
Effect graph
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Relevant supplements heatmap
Relevant supplements sorted by DEX Score.
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SupplementDEX Database
16 supplements for , and rated at least stars. All purchase bands. No minimum star filter.
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Evidence visualised
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Visual summaries of supplement evidence ranked by condition.
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