Necrotising enterocolitis (NEC)
Supplements studied for necrotising enterocolitis (NEC).
Overview
Saccharomyces boulardii (WA 68; medium effect size, high evidence, high trust) has the strongest evidence in this condition, with medium ratings across ten reviewed studies. Oral S. boulardii in preterm infants may reduce NEC risk by about 44% and improve feeding tolerance and hospital stay, though it did not reduce deaths or infections. Regulatory opinions on probiotic use in preterm infants differ.
Lutein, Algal Oil, Vitamin A, and Zeaxanthin (WA 32; very low effect size, low evidence, medium trust) showed no clear NEC prevention in available trials. The heatmap and evidence reviews below compare individual studies.
Effect graph
Subscribe to view effect graphs
Interactive visualisations of ranked conditions and clinical benefit with purchase guidance.
Already a subscriber? Sign in
Relevant supplements heatmap
Relevant supplements sorted by DEX Score.
Subscribe to view effect heatmaps
See effect size, evidence strength, and trust at a glance for every condition.
Already a subscriber? Sign in
SupplementDEX Database
5 supplements for , and rated at least stars. All purchase bands. No minimum star filter.
Subscribe to access the SupplementDEX Database
Read this and 2,600+ other evidence reviews on our practitioner plan.
Already a subscriber? Sign in
Evidence visualised
Subscribe to view condition evidence
Visual summaries of supplement evidence ranked by condition.
Already a subscriber? Sign in