SupplementDEX

Age-related Cognitive Decline

Supplements studied for age-related cognitive decline.

Overview

SupplementDEX indexes 29 supplements for age-related cognitive decline across 126 studies. Several carry medium ratings (WA 60), though findings differ by supplement.

Vitamin B9 (Folate), Acetyl-L-Carnitine, and Phosphatidylserine may help memory and thinking in older adults with mild decline, based on multiple trials. Panax Ginseng is rated medium but often studied in combination products, so ginseng-specific effects remain uncertain.

Ginkgo also carries a medium rating, yet most research shows it does not improve or prevent age-related memory loss in larger, longer trials. Overall evidence is mixed and supplement-specific. See the heatmap and evidence reviews below for ratings across all indexed supplements.

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Relevant supplements sorted by DEX Score.

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SupplementDEX Database

29 supplements for , and rated at least stars. All purchase bands. No minimum star filter.

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