Aging skin
Supplements studied for aging skin.
Overview
Five supplements are indexed for aging skin across 11 studies. Vitamin A has the strongest rating (DEX Score 68, medium effect size, evidence, and trust).
Topical retinol and other vitamin A creams may reduce wrinkles, improve texture and tone, and increase collagen with continued use, though irritation can occur when starting. Astaxanthin (DEX Score 48; low effect size, medium evidence, medium trust) shows mixed results: small oral studies reported improvements in elasticity and moisture, while reviews found no clear effect on wrinkle depth.
Alpha-Lipoic Acid cream, daily avocado intake, and a Vitex agnus-castus combination product each have only low-rated, single-study evidence. See the heatmap and evidence reviews below for full ratings.
Effect graph
Subscribe to access all content
Interactive visualisations of ranked conditions and clinical benefit with purchase guidance.
Already a subscriber? Sign in
Relevant supplements heatmap
Relevant supplements sorted by DEX Score.
Subscribe to access all content
See effect size, evidence strength, and trust at a glance for every condition.
Already a subscriber? Sign in
SupplementDEX Database
5 supplements for and rated at least stars. All purchase bands. No minimum star filter.
Subscribe to access all content
Read this and 2,600+ other evidence reviews on our practitioner plan.
Already a subscriber? Sign in
Evidence visualised
Subscribe to view condition evidence
Visual summaries of supplement evidence ranked by condition.
Already a subscriber? Sign in