High Homocysteine Levels (Hyperhomocysteinemia)
Supplements studied for high homocysteine levels (hyperhomocysteinemia).
Overview
Five supplements are indexed for high homocysteine levels (103 studies). B vitamins dominate: Vitamin B12 and Vitamin B6 both rate high effect size, very high evidence, very high trust (DEX Score 88), and Vitamin B9 (folate) also shows clear homocysteine reductions at about 0.4–5 mg folic acid daily. Vitamin B2 (riboflavin) helps mainly in people with the MTHFR 677TT genotype.
N-Acetyl Cysteine (DEX Score 60) may also lower homocysteine, including in some dialysis populations. See the heatmap and evidence reviews below.
Effect graph
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Relevant supplements heatmap
Relevant supplements sorted by DEX Score.
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SupplementDEX Database
5 supplements for and rated at least stars. All purchase bands. No minimum star filter.
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Evidence visualised
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