SupplementDEX

Carpal Tunnel Syndrome

Supplements studied for carpal tunnel syndrome.

Overview

Carpal tunnel syndrome supplement trials show clearer signals for symptom relief than for function. Alpha-Lipoic Acid may reduce pain in mild-to-moderate cases at 600 mg daily, though hand and wrist function often does not improve; IV-then-oral regimens may help more in some studies.

Topical Flaxseed Oil applied to the wrist alongside night splinting improved symptoms and function in small trials. Oral Vitamin B6 has not shown consistent benefit in higher-quality research despite early positive reports. Acetyl-L-Carnitine and Vitamin B2 (Riboflavin) evidence is limited or combination-based. See the heatmap and evidence reviews below.

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