SupplementDEX

Cyclical Mastalgia

Supplements studied for cyclical mastalgia.

Overview

Evening Primrose Oil is the most-studied supplement here (13 studies, WA 44), but better trials found no clear breast pain reduction versus placebo; some smaller studies suggested possible benefit at 1–4 g daily. One small trial reported more pain relief when combined with vitamin E.

Fish Oil (WA 32; very low effect size, low evidence, medium trust; one study) did not outperform placebo at 3 g daily for six months. Overall evidence is limited and inconsistent for cyclical mastalgia. See the heatmap and evidence reviews below for full ratings.

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SupplementDEX Database

2 supplements for and rated at least stars. All purchase bands. No minimum star filter.

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